Our method RollFISH combining the specificity of single-molecule RNA FISH with the signal enhancement by rolling circle amplification to quantify breast cancer biomarkers in cell lines and tumor samples is now published online!

Michele’s paper on our new method for in situ RNA detection, RollFISH, is accepted in Communications Biology! Congratulations, Michele!

Our book chapter on DNA FISH platform An Application-Directed, Versatile DNA FISH Platform for Research and Diagnostics is now available online.

Our book chapter on BLESS and BLISS Genome-Wide Profiling of DNA Double-Strand Breaks by the BLESS and BLISS Methods is now available online.

Our paper on single-molecule RNA FISH in breast cancer is accepted in Oncotarget! Congratulations to Michele, Erik and Silvano!

“Quantification of HER2 and Estrogen Receptor Heterogeneity in Breast Cancer by Single-Molecule RNA Fluorescence In Situ Hybridization “

Our paper on BLISS is accepted in Nature Communications! Congratulations to Reza, Silvano, Tomek, Quim and Erik! This is the very first paper from our labs!

“BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks”

Nicola co-authors two new publications:

Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction.

Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.