I studied biotechnology and molecular biology, and have more than fifteen years of experience in the wet lab. I am fascinated by the biology of DNA and have a special interest in understanding its spatial arrangement in the cell nucleus. In my daily research, I combine microscopy and sequencing methods with advanced computational tools to explore genome architecture in healthy and diseased cells.

I am a medical doctor and oncologist by education, and a molecular biologist/biochemist by training. My main research topic is genome architecture and stability in connection with cancer and other diseases. I invent new methods that can help us better elucidate the complexity of cancer genomes, with the ultimate goal of improving diagnosis and treatment.

I am originally from England with a background in Intensive Care Nursing. I moved to Sweden with my family in 2005 and have been working at Karolinska Institutet since 2011 as a Personal Assistant and Administrator. I work for two days a week in the Bienko and Crosetto Labs as a Lab Coordinator, mainly dealing with the administrative tasks surrounding purchasing, funding, travel, conference organization and personnel recruitment.

I have a background in biomedical sciences and cancer genomics, and a PhD in 3D genome architecture. As a senior researcher in the Crosetto group, I focus on genome fragility and architecture of (cancer) genomes, for which I apply BLISS, Hi-C, and other methods.

MSc in engineering physics with a PhD in image analysis. I hypothesize and analyze as well as develop software and methods for microscopy images and other biological data related to the organization of the human genome.

My goal is to generate fundamental knowledge to understand first principles on how the 2 meter long genome folds inside of the 10 micrometer size cell nucleus. I am interested in connecting this knowledge to brain disease. My work is multidisciplinary and it combines, genomics, molecular biology, bioinformatics, super resolution microscopy and biophysical simulations.

I have a PhD in medical microbiology and cell biology. Part of my work in BiCro Lab is to manage the lab to be a good research environment for all lab members. For the research part of my work, I am developing multiplex-FISH technologies that can reveal the 3D genome architecture, and can be applied to disease samples for assisting with clinical diagnosis.

I have a background in engineering physics and a PhD in single-cell microscopy. As a postdoc in the BiCro lab, I will work to implement automatized multiplex FISH methods, as well as develop new approaches to reveal the genome architecture in health and disease.

Konstantinos Georgiadis

(Postdoc)
Crosetto/Foukakis Group

I studied medicine in Greece and then moved to the UK where I trained in medical oncology and completed my PhD in liquid biopsies at the Cancer Research UK Manchester Institute. Currently, I work as a postdoctoral fellow shared between the Crosetto group at SciLifeLab and the Foukakis group at Karolinska Institute. I use newly developed next generation sequencing techniques to study clinical samples acquired from patients with breast cancer, aiming to determine the impact of treatment on breast cancer clonal evolution and development of resistance.

I studied Biomedical Sciences at the University of Groningen. My main interest is using the large amount of sequencing techniques available to answer biological questions related to DNA damage and cancer heterogeneity.

I studied chemistry and biology in Hong Kong and then worked in genomics in Japan at the RIKEN Institute. My research interests lie in 3D genome architecture with a particular focus on the interactions between DNA and the other constituents of chromatin – RNA and proteins. I’m working on developing novel technologies to tackle this.

I am a computational biologist trained in quantitative RNA biology. I am fascinated by the complex patterns of gene regulation, for example, through chromatin remodelling, RNA structure and RNA/protein localisation. As a postdoc in Bienko lab, I focus on understanding how eukaryotic genomes are organised into a 3-dimensional structure in the nucleus, what determines the organisation and how the organisation affects gene expression.

I initially joined the BiCro lab as a research assistant and I am excited to now be able to explore different aspects of genome architecture during my PhD. Before coming to Stockholm, I studied in England and in Austria. My background is in biochemistry and physical chemistry.

I have a background in physical chemistry. Before joining BicroLab, I studied genome structure with new single-cell technology in Peking University and West China Hospital. Currently, I’m working on the development of both sequencing techniques and computational methods to decode the hidden logics of genome folding and regulatory networks.

I completed my undergraduate studies in bio-informatics and then received an engineering diploma in biotechnology as well as a Master’s degree in synthetic biology. During my curriculum, I got interested in methods development. Here in the Bienko and Crosetto labs, I am working as a research assistant to focus on FISH methods.

I have a Bachelor of Technology (B.Tech) degree in Genetic Engineering from SRM University, India and University of Miami, United States. Currently pursuing MSc in Molecular Medicine from Uppsala University. I joined BiCro lab for my master thesis and will be involved in developing FISH methods to study DNA-RNA interactions.

I have a MSc in mathematics focusing on network science and topology. My main interest is using abstract mathematical tools such as graph theory and topology to better understand the structure of complex biological systems. As a research engineer in the BiCro lab I am mainly going to work with connectivity data coming from Hi-C experiments. My hope is to both contribute with novel ideas on how to extract information on chromatin folding from Hi-C, but also to learn more about Hi-C analysis in general.

I have a MSc in Life and Health Sciences : Molecular Oncology and Biotherapy from the Faculty of Science and Technology at the University of Limoges, France.
My Master’s education enabled me to acquire conceptual and methodological knowledge combining basic research, clinical research and the development of molecular tools associated with diagnosis and therapy, mainly in the field of oncology.
During my education I became fascinated by 3D genome architecture and its functionality in health and disease. I therefore learned the FISH techniques that I will apply in the context of my work within the Bienko and Crosetto lab.