Current Members

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portugal Hongkong

magda
Magda Bienko
(Principal Investigator)

I studied biotechnology and molecular biology, and have more than fifteen years of experience in the wet lab. I am fascinated by the biology of DNA and have a special interest in understanding its spatial arrangement in the cell nucleus. In my daily research, I combine microscopy and sequencing methods with advanced computational tools to explore genome architecture in healthy and diseased cells.


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Nicola Crosetto
(Principal Investigator)

I am a medical doctor and oncologist by education, and a molecular biologist/biochemist by training. My main research topic is genome architecture and stability in connection with cancer and other diseases. I invent new methods that can help us better elucidate the complexity of cancer genomes, with the ultimate goal of improving diagnosis and treatment.


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Emma Inns
(Lab Coordinator)

I am originally from England with a background in Intensive Care Nursing. I moved to Sweden with my family in 2005 and have been working at Karolinska Institutet since 2011 as a Personal Assistant and Administrator. I work for two days a week in the Bienko and Crosetto Labs as a Lab Coordinator, mainly dealing with the administrative tasks surrounding purchasing, funding, travel, conference organization and personnel recruitment.


Katarina Gradin
(Lab Manager)

I have a PhD in Molecular Biology and have worked at Karolinska Institutet for many years in the field of transcriptional regulation. Most of my time was spent in a research group dedicated to understanding how oxygen levels regulate adaptive gene expression in cells. In this new stage I will work as a lab manager in the Bienko/Crosetto lab, using techniques to study the 3D genome organization.


Xiaoze Li-Wang
(Lab Manager)

I am a biomedical researcher with over 15 years of experience working in various biological laboratories. My background is in Molecular Biology and Immunology, with a PhD in Molecular Virology. As a senior lab manager in the Crosetto and Bienko labs, I will use microscopic methods in combination with the novel methods developed within the groups (iFISH, GP-Seq, etc.) to investigate genomic architecture, in addition to performing routine general lab work.


Federico Agostini
(Postdoc)
Bienko/Crosetto Groups

I studied biotechnologies in Italy, obtained my PhD in Barcelona and did my first postdoc in London. During the years I’ve been working with RNA binding proteins and transcription, but now I’m more focused on understanding how the genome is organized inside the nucleus. To do this, I analyze different sources of data and try to make a sense out of them.


Britta Bouwman
(Postdoc)
Crosetto Group

I have a background in biomedical sciences and cancer genomics, and a PhD in 3D genome architecture. As a postdoc in the Crosetto group, I focus on genome fragility and architecture of (cancer) genomes, for which I apply BLISS, Hi-C, and other methods.



Su Wang
(Postdoc)
Bienko Group

I pursued a higher education in biophysics and biochemistry. My goal within the group is to combine microscopic methods and fluorescent in situ hybridization to investigate the genomic architecture. With such imaging tools, we hope to illuminate the organization of genomes inside the nucleus.



Erik Wernersson
(Senior researcher)
Bienko/Crosetto Groups

MSc in engineering physics with a PhD in image analysis. I hypothesize and analyze as well as develop software and methods for microscopy images and other biological data related to the organization of the human genome.


Roberto Ballarino
(PhD Student)
Crosetto Group

I am a neurobiologist with training in induced pluripotent stem cell technology. The focus of my research lies on studying genome instability and architecture across neurodevelopment. I investigate genome-wide DNA double-strand breaks with the aim of characterizing neural regulation of gene expression in relation to brain development and disease.


Eleni Gelali
(PhD Student)
Bienko Group

I have a background in Molecular Biology and Genetics. I am fascinated by the enigma of nuclear architecture and especially interested in the genome organization changes during early embryonic development and differentiation. Together with my colleagues, I employ and develop microscopy-based techniques in an effort to study those questions.


Gabriele Girelli
(Postdoc)
Bienko Group

I am a biotechnologist by education, training as a bioinformatician on sequencing and imaging data analysis. My field of interest is genome architecture, focusing on the radial organization of the genome and FISH data analysis. I also have an interest in cancer and tumor heterogeneity. I like to use my skills to develop user-friendly informatics tools to empower the research community.


Ana Mota
(PhD Student)
Bienko Group

I am a bioengineer by training and my main interests are focused on developing biological technologies or techniques. In the lab I aim to improve the FISH versatility in order to extract more information regarding genome architecture.


Michele Simonetti
(PhD Student)
Crosetto Group

I am a medical biotechnologist that tries to combine a diagnostic background with research. My main research topic is intra-tumor heterogeneity both at the phenotypic and genetic level. My final goal is to better understand the complexity of tumors to improve their classification and treatment.


Luuk Harbers
(PhD Student)
Crosetto Group

I studied Biomedical Sciences at the University of Groningen. My main interest is using the large amount of sequencing techniques available to answer biological questions related to DNA damage and cancer heterogeneity.


Eleonora Oliani
(Research Assistant)
Bienko Group

I have recently graduated in medical biotechnology and joined the BiCro lab as a research assistant. I will be working on method development to answer the many questions related to genome architecture. I’m eager to learn the interesting novel techniques developed in the lab, and to improve my skills as a researcher.


Wing Hin Yip
(PhD Student)
Bienko Group

I studied chemistry and biology in Hong Kong and then worked in genomics in Japan at the RIKEN Institute. My research interests lie in 3D genome architecture with a particular focus on the interactions between DNA and the other constituents of chromatin – RNA and proteins. I’m working on developing novel technologies to tackle this.


Yajing Zhu
(Visiting PhD Student)
Crosetto Group

I am a surgeon by training and I also have working experience in innovative pharmaceutical company where I focused on cancer drug development. My main research interest is translational medicine which allows me to seek to narrow the gap between basic science and clinical practice and finally benefit all the patients.


Sofia Onorato
(Erasmus Student)
Crosetto Group

I am currently attending my final year in the Bachelor’s degree in Biotechnology at the University of Udine. Throughout my studies I have developed a strong interest in Bioinformatics and matured the desire to specialise in this field. During the Erasmus+traineeship in the BiCro lab I will focus on elucidating the single-cell copy number profiles and genome architecture of various cancer types.


Wenjing Kang
(Postdoc)
Bienko Group

I am a computational biologist trained in quantitative RNA biology. I am fascinated by the complex patterns of gene regulation, for example, through chromatin remodelling, RNA structure and RNA/protein localisation. As a postdoc in Bienko lab, I focus on understanding how eukaryotic genomes are organised into a 3-dimensional structure in the nucleus, what determines the organisation and how the organisation affects gene expression.


Gertjan Laenen
(Visiting PhD student)
Bienko Group

I completed a Masters in Molecular Biology and Physiology at the KU Leuven in Belgium after which I decided to continue in research. Having a keen interest in the interplay of physical factors in a biological system, brought me to pursue a PhD in the lab of Angela Taddei at the Curie Institute in Paris where I’m studying the dynamics of genome reactivation upon quiescence exit in Baker’s yeast. This process occurs through a rapid and large scale genome reorganization and a part of my PhD is to assess differences in the radial positioning of genomic regions during this transition. To achieve this, I’m trying to adapt GPseq to our yeast model system.


Gesa Voigt
(Erasmus student)
Bienko Group

I am currently in my final year of the Bachelor’s program for Molecular Medicine at the university of Göttingen, Germany. Being fascinated by the results of fluorescent microscopy, I would like to gain experience in DNA FISH and other staining techniques. During my summer internship, I want to apply these methods to studying the changes in 3D genome arrangement in neuronal cell cultures.