Current Members

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magda
Magda Bienko
(Principal Investigator)

I studied biotechnology and molecular biology, and have more than fifteen years of experience in the wet lab. I am fascinated by the biology of DNA and have a special interest in understanding its spatial arrangement in the cell nucleus. In my daily research, I combine microscopy and sequencing methods with advanced computational tools to explore genome architecture in healthy and diseased cells.


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Nicola Crosetto
(Principal Investigator)

I am a medical doctor and oncologist by education, and a molecular biologist/biochemist by training. My main research topic is genome architecture and stability in connection with cancer and other diseases. I invent new methods that can help us better elucidate the complexity of cancer genomes, with the ultimate goal of improving diagnosis and treatment.


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Emma Inns
(Lab Coordinator)

I am originally from England with a background in Intensive Care Nursing. I moved to Sweden with my family in 2005 and have been working at Karolinska Institutet since 2011 as a Personal Assistant and Administrator. I work for two days a week in the Bienko and Crosetto Labs as a Lab Coordinator, mainly dealing with the administrative tasks surrounding purchasing, funding, travel, conference organization and personnel recruitment.


Federico Agostini
(Postdoc)
Bienko/Crosetto Groups

I studied biotechnologies in Italy, obtained my PhD in Barcelona and did my first postdoc in London. During the years I’ve been working with RNA binding proteins and transcription, but now I’m more focused on understanding how the genome is organized inside the nucleus. To do this, I analyze different sources of data and try to make a sense out of them.


Britta Bouwman
(Postdoc)
Crosetto Group

I have a background in biomedical sciences and cancer genomics, and a PhD in 3D genome architecture. As a postdoc in the Crosetto group, I focus on genome fragility and architecture of (cancer) genomes, for which I apply BLISS, Hi-C, and other methods.


Joaquín Custodio
(Postdoc)
Bienko Group

I hold a Master’s degree in Immunology and a PhD in epigenomics. In the lab, I am developing new techniques to study the radial organization of the genome in the cell nucleus. I am applying these new techniques to study how genome radial organization is disrupted in various diseases, such as cancer.



Silvano Garnerone
(Senior Researcher)
Crosetto Group

I am a physicist by training, now interested in what machine learning and information theory can teach us about cancer genomes. I take care of the data management and analytics in the group, and I contribute to develop biological insights from the analysis.



Marcin Nicos
(Postdoc)
Crosetto Group

I studied in Poland where I obtained my MSc and PhD in molecular biology. During my postdoc in the Crosetto group I am studying lung cancer brain metastases using a combination of genomic and high-throughput microscopy assays.



Su Wang
(Postdoc)
Bienko Group

I pursued a higher education in biophysics and biochemistry. My goal within the group is to combine microscopic methods and fluorescent in situ hybridization to investigate the genomic architecture. With such imaging tools, we hope to illuminate the organization of genomes inside the nucleus.



Erik Wernersson
(Senior researcher)
Bienko Group

MSc in engineering physics with a PhD in image analysis. I hypothesize and analyze as well as develop software and methods for microscopy images and other biological data related to the organization of the human genome.


Xiaolu Zhang
(Postdoc)
Crosetto Group

I was educated as medical doctor and hematology specialist in college and then trained in the field of oncology during my PhD at Karolinska Institutet. My main research focus is developing novel genomic and transcriptomic methods that are suitable to investigate intra-tumor heterogeneity of solid tumors.


Roberto Ballarino
(PhD Student)
Crosetto Group

I am a neurobiologist with training in induced pluripotent stem cell technology. The focus of my research lies on studying genome instability and architecture across neurodevelopment. I investigate genome-wide DNA double-strand breaks with the aim of characterizing neural regulation of gene expression in relation to brain development and disease.


Eleni Gelali
(PhD Student)
Bienko Group

I have a background in Molecular Biology and Genetics. I am fascinated by the enigma of nuclear architecture and especially interested in the genome organization changes during early embryonic development and differentiation. Together with my colleagues, I employ and develop microscopy-based techniques in an effort to study those questions.


Gabriele Girelli
(PhD Student)
Bienko Group

I am a biotechnologist by education, training as a bioinformatician on sequencing and imaging data analysis. My field of interest is genome architecture, focusing on the radial organization of the genome and FISH data analysis. I also have an interest in cancer and tumor heterogeneity. I like to use my skills to develop user-friendly informatics tools to empower the research community.


Tomasz Kallas
(PhD Student)
Bienko Group

I am a Biotechnologist by training. My interest lies in developing new methods for better understanding of the nuclear architecture.


Reza Mirzazadeh
(PhD Student)
Crosetto Group

I hold a master’s degree in genomics and bioinformatics, and am passionate about developing new molecular tools for the life sciences. I developed the BLISS method for genome-wide DNA double-strand breaks profiling (Yan, Mirzazadeh et al., Nature Communications 2017) and I am applying it in different model systems to understand better the biology of genome fragility and its roles in health and disease.


Ana Mota
(PhD Student)
Bienko Group

I am a bioengineer by training and my main interests are focused on developing biological technologies or techniques. In the lab I aim to improve the FISH versatility in order to extract more information regarding genome architecture.


Michele Simonetti
(PhD Student)
Crosetto Group

I am a medical biotechnologist that tries to combine a diagnostic background with research. My main research topic is intra-tumor heterogeneity both at the phenotypic and genetic level. My final goal is to better understand the complexity of tumors to improve their classification and treatment.


Maud Schweitzer
(Research assistant)

I am trained as a laboratory technician and I am specialized in various molecular and cellular biology techniques. My work in the team is focused on applying FISH methods to study genome architecture.


Sólrún Kolbeinsdóttir
(Research assistant)

I have a bachelor’s degree in molecular biology and biochemistry, and a master’s degree in biomedicine. My scientific interests are answering fundamental cell biology questions. I study genome architecture with imaging and sequencing methods.


Luuk Harbers
(Erasmus Student from the Netherlands)
Crosetto Group

I am a Biomedical Sciences Master student at the University of Groningen. My main interest is using the large amount of sequencing techniques available to answer biological questions related to DNA damage and cancer heterogeneity.


Cecilia Derory
(Visiting Student from France)
Crosetto Group

I am a second-year undergraduate student at ESTBB in France and I prepare a diploma of laboratory technician in Biology, Biochemistry and Biotechnology. In the lab, I work on the visualization of intra-tumour heterogeneity in lung cancers and matched brain metastases.


Mukhar Jain
(Visiting student from India)
Bienko Group

I am a second year student at IIT Delhi, pursuing B.Tech in Biochemical Engineering and Biotechnology. In the lab, I am developing machine learning methods to improve the analysis of DNA and RNA FISH images.


Sudhish P
(Visiting student from India)
Bienko Group

I am a junior undergrad from IIT Delhi, pursuing B.Tech in Biochemical Engineering and Biotechnology. In the lab, I am working on machine learning to improve analysis of DNA/RNA FISH data.


Gabriel Felicio Dos Santos
(Visiting Student from Brasil)
Crosetto Group

I am a fourth-year medical student in Brazil, aiming a surgical career. My interest comprise biochemistry and neurobiology, mainly associating research with clinical knowledge.